The Tragic Origins of Ginny’s Sapphire Disease

For the first time, we see Ginny in a flashback from Kuma’s past, revealing that her Sapphire Disease has a deeply tragic origin. Ginny was forced into an unwanted marriage with the Celestial Dragon, Saint Charlos. She had been living in Mary Geoise for many years before ultimately being coerced into pregnancy. Her daughter, Bonney, also suffers from the same disease inherited from her mother.
The disease manifests through widespread blue patches across the body, leading to death. After contracting this illness, Ginny has been in denial about her condition and undertakes a desperate journey back to the Sorbet Kingdom, hoping to leave Bonney in Kuma’s care.
This Sapphire Disease worsens upon exposure to natural light, rapidly accelerating the decline towards death. Despite trying to avoid sunlight, the afflicted individuals cannot escape its grasp, as it merely slows the progression of the disease. Due to her Sapphire Disease, Bonney was not exposed to sunlight after her birth. Kuma plays a vital role in prolonging Bonney’s life, managing her illness and extending her survival into another decade.
The Sapphire Disease: A Hidden Threat in One Piece

The Sapphire Disease is the result of failed experiments. Ginny is a survivor of these experiments, showcasing the disease in a debilitating form that ultimately gets passed down to her daughter, Bonney. The campaign to end the disease quickly becomes a sacrifice and a heroic journey, with the turning point being the grafting of Bonney’s life force onto Vegapunk’s experimental creation.
The origins of Sapphire Disease have finally been revealed. It was created by Saturn, a long-standing scientist who has conducted various experiments in the One Piece universe. The subjects of Saturn’s experiments, including Ginny, bear the heavy burden of the consequences of these failed experiments. Every interaction between Saturn and the Sapphire Disease raises questions about the ethics and methods of the Celestial Dragons.
The potential causes of the disease linked to Saturn could relate to scientific knowledge or the malevolent desires of the Celestial Dragons. This revelation prompts inquiries into whether the powers held by other members of the Celestial Dragons are similar. Each individual is nearly tied to a planet and the unique abilities associated with it.
As evidenced by Law’s encounter with the disease, the Sapphire Disease appears on a planetary scale and emerges as a hidden threat within the One Piece universe. There are speculations that Saturn or another Celestial Dragon member may be the source behind this disease. This connection illustrates the intricate relationships between these characters and the emergence of related diseases.