In the 700 chapters of the manga Naruto, the creator Masashi Kishimoto introduced many ninja techniques with various unique abilities and differing strengths. Several techniques in this series possess the capability to cause significant destruction. This raises the question: which technique is the most dangerous, causing the most devastating damage in the entire history of the ninja world?
First and foremost, it is essential to clarify that we will focus solely on techniques aimed primarily at annihilating the surroundings. Therefore, techniques like the Tsukuyomi, which can only trap an opponent, will not be considered. The primary function of Tsukuyomi is to trap a target in an endless illusion.
Based on what has been depicted and presented in Naruto, the Jutsu with the most extensive destructive capability is the Expansive Truth-Seeking Ball. This is the ultimate ability used by Kaguya during the battle against Team 7 in the Fourth Great Ninja War.

There are three ways to obtain Truth-Seeking Balls in Naruto. The two most common methods involve using the chakra of the Sage of Six Paths or transforming into the Jinchuriki of the Ten-Tails. The third method is utilizing the immense power of the Tenseigan user. These orbs are palm-sized, black in color, and the user can manipulate and change their shapes for various purposes.
The Truth-Seeking Balls contain terrifying destructive power. However, these orbs are powerful enough that they can eliminate entire adversaries instantaneously. According to Hiruzen Sarutobi, they operate quite similarly to the legendary Sage Art: Super Great Ball.

Kaguya enhanced the capabilities of the Truth-Seeking Balls by utilizing the chakra of her own body and the chakra of the shinobi in the Infinite Tsukuyomi, creating the Expansive Truth-Seeking Ball to generate a new dimension.
According to the Naruto Databook, the Expansive Truth-Seeking Ball can sweep across the entire universe in a non-space-time manner, highlighting the extreme danger of this technique.